| Attention – As of Monday 12/16/2024, all new UConn/BRANY cede submissions will originate in InfoEd. To initiate the local UConn cede review process, which investigators must complete prior to submitting directly to the BRANY IRB, follow these steps:
1. Create a new initial application in the Human Subjects/IRB section of InfoEd.
2. In the General Information section at the top of the application, select the option “Request to rely on non-UConn IRB” when prompted to answer, “What type of IRB review are you requesting?”
3. In the External IRB Information section of the application, select “BRANY IRB” when prompted to answer, “What type of external IRB is proposed to review this study?”
4. Follow all other prompts within the application to complete and submit the cede submission.
Emailed UConn/BRANY cede submissions will no longer be accepted at irb-reliance@uconn.edu beginning 12/16/24. |
UConn has designated BRANY IRB as its IRB for externally funded research and certain multisite studies. BRANY IRB is an independent IRB that is not affiliated with UConn. For BRANY IRB-reviewed studies, the UConn study team completes the submission to BRANY IRB through the IRB Manager online submission system and BRANY IRB conducts the ethical review on behalf of UConn. Study teams must also submit a cede application to the UConn IRB so that UConn can track the research conducted at UConn and ensure all local requirements are met.
Studies that will be reviewed by BRANY IRB:
- Externally Funded Research
- Human subjects research that has external funding support (e.g., grant, contract, foundation). This applies to exempt, expedited, and convened (a.k.a. full) review types. This also includes externally funded multisite research and research involving external investigators or staff; OR
- Multisite Research/External Investigators
- Studies that involve more than 2 external sites or external investigators/staff for which single IRB (by UConn/BRANY) is being requested. This applies to externally funded, internally funded, and unfunded research. PLEASE NOTE: This refers to collaborating researchers/study personnel, not facilities that may be sites where research activities occur.
BRANY Submission Process
- Review the Determine Eligibility for BRANY IRB Review to confirm your project qualifies for BRANY IRB review.
- Review the UConn/BRANY Process Overview for detailed instructions for creating a BRANY IRB submission.
- Submit the documents required for UConn local context review as a “Request to rely on a non-UConn IRB” InfoEd application.
- Once local approvals are complete, submit the complete BRANY IRB application package to BRANY IRB.
UConn IRB’s role in BRANY IRB-reviewed studies
UConn IRB will verify that all local institutional requirements are met via a local submission, including:
- study team training requirements
- ancillary reviews
BRANY IRB Review Contacts
| Name | Phone | ||
| UConn IRB Reliance | irb-reliance@uconn.edu | ||
| BRANY IRB Contact | Vanessa Rodriguez | 516.514.2445 | vrodriguez@brany.com |
BRANY IRB Template Documents
SBR Consent Template Instructions
Exempt Consent Template Instructions
Training Information
BRANY IRB Manager Training Information: https://www.brany.com/irb-manager/
BRANY FAQs
| What is meant by “External Site?” |
| This refers to collaborating researchers/study personnel, not facilities that may be sites where research activities occur. This does not mean a site/location where UConn researchers may be conducting research activities. |
| What is meant by “Single IRB (by UConn/BRANY) is being requested?” |
| This refers to a situation where the UConn study team is requesting that the external sites/personnel cede IRB review to UConn and that UConn/BRANY serve as the IRB of record for these sites. If the external sites will have their home IRB review the study, then those sites would not satisfy the more than 2 external sites requirement. Please note that single IRB review is required for most federally-funded studies. |
| What should I do if an external IRB is planning to serve as the single IRB of record for a multisite study where I will be engaged in human subjects research? |
| If an external IRB will be the single IRB of record for your multisite study, please submit a “Request to rely on a non-UConn IRB” application in InfoEd to initiate a request to rely on a non-BRANY external IRB. The UConn IRB’s reliance team will review your request and help you to facilitate a reliance agreement between UConn and the reviewing IRB. If another IRB will be the single IRB of record, the study should not be submitted to BRANY. |
| What are BRANY IRB review turnaround times? |
| Please contact Vanessa Rodriguez, BRANY IRB’s liaison with UConn, for information on BRANY turnaround times. |
| How quickly will UConn’s Reliance Team review a request to cede IRB review to BRANY? |
| IRB Reliance will work to review cede requests within one week of receipt. |