This is a reminder that certain new studies (as noted below) should be submitted to BRANY IRB instead of the UConn IRB.

• Externally funded research (including when the award is expected but is pending)
• Multisite Research/External Investigators: Studies that involve more than 2 external sites or external investigators/staff for which single IRB (by UConn/BRANY) is being requested. PLEASE NOTE: This refers to collaborating researchers/study personnel, not facilities that may be sites where research activities occur.
  • What is meant by “Single IRB (by UConn/BRANY is being requested”?
    • This refers to a situation where the UConn study team is requesting that the external sites/personnel cede IRB review to UConn and that UConn/BRANY serve as the IRB of record for these sites. If the external sites will have their home IRB review the study, then those sites would not satisfy the more than 2 external sites requirement. Please note that single IRB review is required for most federally-funded studies.
  • What should I do if an external IRB is planning to serve as the single IRB of record for a multisite study where I will be engaged in human subjects research?
• If an external IRB will be the single IRB of record for your multisite study, please complete the External Involvement/Reliance Intake Form for Non-UConn Research Sites (found on the IRB-Reliance – General) webpage and email it to irb-reliance@uconn.edu. The UConn IRB’s reliance team will help you to facilitate a reliance agreement between UConn and the reviewing IRB. If another IRB will be the single IRB of record, the study should not be submitted to BRANY.

Instructions, forms, and templates for submissions to BRANY IRB are available on our website under the tab for IRB Reliance. If you are unsure which IRB to apply to, or have questions about the process, please reach out to the IRB Reliance Team at irb-reliance@uconn.edu.

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